Filling Ihenacho's spot on the taxi unit will be former Cowboys CB Mario Butler, who has been active for one game since signing with Dallas as an undrafted rookie last year.
Elsewhere in the AFCW, QB Brady Quinn has been ruled out for Thursday night's Chiefs/Chargers game after suffering a concussion against Oakland.
The return from suspension of D.J. Williams after the Broncos' Week 10 game at Carolina has created questions about how the team will handle its LB corps going forward.
Unfortunately, a fractured fibula suffered by Joe Mays will go a long way to forcing Denver's hand there. Mays is done for the year after he was injured during a Broncos punt return last night, and is expected to be placed on IR tomorrow.
Mays had lost his starting Mike job to Keith Brooking, and had been relegated to special teams duty for the past two weeks. 2011 sixth-rounder Mike Mohamed is on the practice squad as a likely replacement for Mays, if a temporary one until Williams is reinstated.
The former Saint had suffered a seizure in August, and was held back from traveling to San Diego for Denver's last game due to a recurrence of symptoms that had preceded the earlier seizure.
Nine Broncos are on the final injury report for Week 6, and all are listed as probable, after all 53 players on the active roster were full participants in Saturday's practice. Ryan Clady was back in action after missing Friday's work due to a minor hamstring injury.
The outlook for the Chargers is not looking as good, as kicker Nate Kaeding is out, starting left tackle Jared Gaither and nickel corner Shareece Wright are doubtful, and wideouts Eddie Royal and Malcom Floyd are both listed as questionable. RB Ryan Mathews and RT Jeromey Clary are probable.
Reed was signed by Cleveland as an undrafted rookie out of Florida State; Weems was an undrafted signee by the Vikings out of Oregon, and he was on Indy's practice squad for the first two weeks of this season.
The Broncos had two open spots on the practice unit following last weekend's promotion of Mohamed and Duke Ihenacho to the 53-man roster. G Adam Grant was waived from the practice squad to create the third open spot for today's additions.
As expected, the Broncos have placed center J.D. Walton on injured reserve with a fractured/dislocated ankle.
Taking his place on the active roster will be linebacker Joe Mays, who returns after serving a one-game suspension for his Week 3 hit on Texans QB Matt Schaub.
Tight end Virgil Green, who is back working with the team after serving a four-game PED-use suspension, was also reinstated to the active roster.
Updated 7:59pm ET
Second-year safety Quinton Carter was placed on IR and will undergo microfracture surgery next week on the same knee he had arthroscopically repaired during training camp.
With Joe Mays suspended for tomorrow's game against Oakland, two spots had opened on the active roster; Denver promoted safety Duke Ihenacho and linebacker Mike Mohamed to fill them.
The Broncos have re-signed linebacker Mike Mohamed to their practice squad today; Jacksonville had waived him from their PS yesterday, two weeks after having signed him.
To make room for Mohamed, their own 2011 sixth-round pick, Denver waived TE Cornelius Ingram.
With the one-game suspension of Joe Mays and the injury to Nate Irving (concussion), Denver is currently down to five healthy linebackers. Von Miller, Keith Brooking, and Wesley Woodyard are expected to start on Sunday, with sixth-rounder Danny Trevathan and undrafted rookie Stephen Johnson as backups.
Manny Ramirez's days functioning as a turnstile along the Broncos offensive line are nearing an end.
Right guard Chris Kuper has returned to participate in today's padded practice, raising hopes that he will be available on at least a part-time basis on Sunday against Oakland. However, Lindsay Jones says the seventh-year player is unlikely to dress Sunday.
Ramirez is the only of Denver's five starting offensive linemen to receive a negative overall score from PFF (-5.3), although he did grade out at +2.1 for the opening win over Pittsburgh.
The Broncos are placing fourth-round pick center/guard Philip Blake on IR, and promoting center C.J. Davis from the practice squad to take his place on the 53-man roster. Adam Grant, who spent the 2011 season on Denver's practice squad, will rejoin the group in place of Davis.
Blake was inactive for Denver's first two games and was listed on the team's injury report as having a "Thump" issue which limited his practice on Saturday. So, either thump injuries are a big deal, or something else has happened to Blake.
Davis made the team out of training camp but was cut loose to facilitate the addition of veteran center Dan Koppen.